PQQ, The Mitochondrial Micronutrient – Benefits, Mechanism of Action, Potential Side-Effects, & Dosage

PQQ, The Mitochondrial Micronutrient – Benefits, Mechanism of Action, Potential Side-Effects, & Dosage

PQQ, also known as Pyrroloquinoline quinone, is a redox cofactor, an essential micronutrient found in most foods. A cofactor means that the PQQ helps the enzymes accomplish their jobs. As always, there are some foods where this micronutrient is found in much greater amounts as compared with others, including spinach, green tea, parsley, kiwi fruit, green peppers and so on. The PQQ is also found in the human breast milk, and humans are even able to synthesize a small amount of PQQ in their bodies as well, although not in an amount that is enough to satisfy the body's needs which is why it must be introduced through food and supplementation. We say an essential micronutrient because of the numerous beneficial effects that it poses when introduced to the human body. Because more often than we should, we fail at introducing the right amounts of PQQ to our bodies, there is a quality PQQ supplement that we can lean on to. In the following post, we will talk about this supplement and everything that you need to know about it.

Overview of PQQ

PQQ supplements are considered to be the best cognition and energy boosting supplement that we have today. From improved mood, sleep quality, cognitive performance, and wakefulness the beneficial effects of the PQQ are numerous. The PQQ supplements, added to your normal diet, can make some serious changes in your wellbeing. They have antioxidant properties, and they are able to aid the formation of new mitochondrial cells. That means that the PQQ supplement will help you reduce any present inflammation, improve your sleep quality, lower your cholesterol levels, boost your cognitive functions and much more. And you will get all of that in one bottle of PQQ supplements which can be bought online or at your favorite market!

The PQQ has been first found back in 1979 when the researchers back then discovered this new coenzyme that they considered to be a probable cofactor for many enzymatic reactions in bacteria. Since then, its beneficial effects could not be reversed.

How Does it Work?

Once it is introduced in the human body, through the bloodstream, the PQQ is transferred to all cells in order to promote the growth of new mitochondria and achieve all of its beneficial effects. The exact mechanism of the act of the PQQ supplement is yet to be clearly defined.

Beneficial Effects of PQQ

  • 1. Reduces Fatigue
  • PQQ supplements are known to solve the sleep problems that many people battle with nowadays. As you probably know and possibly have experienced this in the past when you are not getting enough quality sleep, your body battles with fatigue day after day. Fatigue is what prevents you from engaging in the normal everyday activities and causes your mood to become worse and worse with each night spend without any sleep. By improving your sleep quality, the PQQ supplements will help you win your battle against fatigue once and for all.


  • 2. Increases Energy Levels Throughout the Mitochondrial Optimization

  • PQQ is referred to as “optimal regulator” when it comes to its role in mitochondrial optimization. The PQQ has been scientifically proven to be able to stimulate the right genes responsible for promoting mitochondrial and cellular respiration, growth and proliferation. The PQQ is able to stimulate mitochondrial biogenesis and with it brings all sorts of positive effects including the elimination of free radicals, increasing energy levels, and increased longevity of life.



  • 3. Increases Sleep Quality

  • The PQQ supplement is perfect for anyone who is experiencing difficulties while falling asleep. The PQQ guarantees to improve your sleep quality, lessen the time needed to fall asleep and with that improve your mood, appetite, and pain ratings which are all linked to your quality of sleep.


  • 4. Increases Heart Health

  • Patients who have suffered a heart attack in the past should seriously consider taking a quality PQQ supplement. That is because the PQQ supplements have been scientifically proven to be able to reduce the size of the damaged areas that result from the acute heart attack. It has been proven that this happens when the PQQ supplement has been given before as well as after the heart attack itself.

    Potential Side-effects

    The highest tested dose in rats – 100mg/kg/day has caused no side effects to develop, based on the most recent findings. On the other hand, although it has not been scientifically tested or proven, some former users of the PQQ supplements have reported feeling mild headaches and sleep problems, mostly insomnia symptoms, as a result of their experience with PQQ supplements. Once again, this has not been scientifically tested and proven. We cannot be sure whether or not the PQQ supplements cause any side-effects to occur in humans, and when they do, what side-effects should we expect.

    If you are using any other medication at the moment, please do consult your doctor. It is unknown whether or not the PQQ supplements interact with other medications and if they do, what effects would be expected to occur. Please report any medical conditions and issues that you might be suffering from as well as any other medications that you might be using at the moment before you proceed with talking PQQ supplements.

    Suggested Dosages

    The optimal dose of PQQ supplements is yet to be determined. However, there are some suggested dosages based on the problem that you are trying to solve with the use of the PQQ supplement. For example, 0.075 to 0.3 mg/kg/day is the recommended dosage for enhancing your mitochondria. On the other hand, for reducing present inflammation in the body, a dosage of about 20mg/day is considered to be enough. PQQ supplements are recommended to be taken once or twice on a daily basis. However, there is no information available on whether or not should these supplements be taken with or without food. For more information on this topic, please consult your doctor.

    Overall Summary

    PQQ is an essential micronutrient which although it is introduced through food, it should be taken in the form of a supplement as well. Why do you ask? It is because of the fact that this little coenzyme poses numerous beneficial effects that will help you improve your energy levels, cognition functions, mood, and sleep quality, among many others as well. Not to mention the fact that it causes no known side-effects, as reported by its former users so far! Do not miss out on the opportunity to include this amazing supplement in your life and improve your general health and wellbeing!


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